Relistor Information:

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Relistor (Generic name: Methylnaltrexone Bromide) is the FIRST approved medication for opioid-induced constipation (OIC), which caused by opioid drugs (e.g., codeine, hydromorphone, morphine) used for pain relief in patients with advanced illness who are receiving palliative care and usual laxative therapy has not been sufficient. Methylnaltrexone Bromide is special narcotic (opioids) drug that blocks certain effects of other narcotic medicines. It works by reducing constipation and pain-relieving effects of narcotic medications.

Relistor is available in single-use vial for subcutaneous injection in the upper arm, stomach, or thigh. Bowel movements may occur within 30 minutes, so make sure you have the access to toilet facilities after Relistor injection. Use Relistor subcutaneous injection exactly as prescribed.

Relistor Side Effects:

The most common Relistor side effects are abdominal cramp, diarrhea, dizziness, drowsiness, gas, headache, nausea, vomiting, and injection site reactions (e.g., burning, pain, redness, stinging). If you are experiencing any severe side effects such as chest pain fever, jaundice, mood changes, urination pain, vision changes, and signs of allergic reaction (e.g., difficult breathing; hives; rash; swelling), please inform your doctor immediately.

Relistor Precautions:

Do NOT use Relistor injection if you are allergic to Methylnaltrexone or any of the ingredients in Relistor medication. Relistor should not be given more than once every 24 hours. Before using Relistor, tell your doctor if you have had any medical conditions such as blockage in stomach or intestines, severe diarrhea. The Relistor treatment may increase the changes of multiple births. Tell your doctor about all the prescriptions and over-the-counter (OTC) medications you use. They may interact with Relistor drug, especially of: other narcotic pain medications. Consult your doctor if you are pregnant or breast-feeding.

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