Archive for December, 2011

Plavix or Esbriet?

Friday, December 30th, 2011

from Armchair Mogul

A new study suggests the generic test will not help physicians determine if patients should get Plavix, published in the Journal of the American Medical Association. In the recent findings from 32 studies that involved about 42,000 patients, gene variant patients did not reveal a significantly increased rate for heart attack and stroke.

In 2010, FDA gave a boxed warning to Plavix that the drug has the reduced effectiveness in preventing heart attacks in patients with a certain gene variant. About 30 percent of the US population has the gene variant.

Plavix, also known as clopidogrel, is the most prescribed anti-coagulant drug used to treat blood clot and prevent heart disease and stroke.

Fast Facts of Plavix
• $5.4 Billion of Plavix sales in the first three quarters of 2011
• $6.7 Billion in global sales in 2010
• About 40 million people take the drug worldwide
• Second biggest selling drug after Lipitor

Generic version of Plavix is available when the brand expires in 2011. Some researcher thinks the generic testing may help physician choose between generic Plavix and the new rival drug Effient. More information, read the full article: Doubt Cast on Use of Genetic Test Before Plavix.

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Generic Version of Teveten Approved by FDA

Wednesday, December 28th, 2011

Pittsburgh – Mylan Inc. recently had received FDA approval for the generic hypertension drug, Teveten.

Teveten, or eprosartan mesylate, is marketed by Abbott Laboratories Inc. Mylan said Teveten’s U.S. sales totaled $4.9 million over the year ended Sept. 30.

Mylan said it is now shipping generic Teveten in strengths of 400 milligrams and 600 milligrams. It will have six months of marketing exclusivity.

For more information about Mylan, please visit www.mylan.com. To buy Teveten online, please check the product details here.

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Canadian Researchers Close to Developing an Ovarian Cancer Vaccine

Friday, December 23rd, 2011

from stevendepolo

Researchers based out of the B.C. Cancer Agency’s Deeley Research Centre have stated they are that much closer to creating a vaccine to fight ovarian cancer. This new vaccine would work differently then the usual preventative vaccine.

Ovarian cancer, the most severe of the gynecological cancers, kills over 1700 Canadian women annually. Ovarian cancer affects the ovaries, the egg-producing centers in women’s bodies. If left undiagnosed, cancerous cells are often shed from the ovaries, affecting the organs and structures around them, such as the uterus, bladder and bowel.

Currently, no screening tools, (such as a mammogram for breast cancer) are available for ovarian cancer. What symptoms there are are often vague and easily missed. Because of this, ovarian cancer is often missed until it is in advanced stages; where it often has adversely affected other parts of the body.

Ovarian cancer is usually treated in stages, starting with tumor removal. After the cancerous tumor is surgically removed, the patient undergoes intense chemotherapy sessions. This often knocks back the cancerous cells, but many patients see a relapse in two to three years.

Researchers would ideally use the vaccine at this point, after chemotherapy, when the cancerous cells are at their weakest, with the lowest count. The Deeley Research vaccine would work by educating the patient’s own immune system to attack the cancerous cells. They would tailor each patient’s vaccine by using cells from their tumor. This provides a more targeted attack on the mutated cells.

If the cancerous cells again mutate, another targeted vaccine could be easily created, says Brad Nelson, project leader, and a cellular and molecular biologist. “There really is no limit to how long you can play this strategy.”

Although researchers are three to five years away from clinical trials, the formula is sound. The vaccine will target five of the cancer cells various mutations. The chance that the cancer virus is able to bypass all five attacks by the body’s immune system is low.

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HIV Vaccine has Been FDA-Approved for Human Trials

Wednesday, December 21st, 2011

from iStockphoto

An HIV vaccine created by Canadian researchers has just been approved by the FDA for human clinical trials. University of Western Ontario professor and researcher Dr. Chil-Yong Kang stated, “FDA approval for human clinical trials is an extremely significant milestone for our vaccine, which has the potential to save the lives of millions of people around the world by preventing HIV infection.”

Although other types of Human Immunodeficiency Virus vaccines have been tested before, the UWO-created vaccine is the first to use a whole killed virus in the composition of its vaccine. In early testing, the vaccine created a strong immune response, with no adverse effects, the researchers proudly stated.

The vaccine, named SAV001, will now have to undergo the US Food and Drug Administration’s rigorous human trial protocols, starting with phase 1. In January of 2012, the vaccine will be retested for safety on 30 HIV-positive volunteers. After the retest is completed and deemed safe, the researchers will enact the next step in their vaccine’s trials. In phase 2, researchers will examine their subjects’ immune responses to the vaccine. This will involve 600 HIV-negative volunteers. They are taking a huge risk in exposing themselves to the live virus. Phase 3 will continue data collection to determine the efficacy of the vaccine. In this phase they will test it on 6000 high-risk volunteers.

To read the full article, please >Click< here.

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Big Mountain Drugs Unveils New Video for the Online Ordering Process

Monday, December 19th, 2011

Big Mountain Drugs, a leading Canadian pharmacy, has proudly released a new instructional video detailing their online drug ordering process. Big Mountain Drugs chose the video format in order to communicate with their wide array of customers. “We have decided to offer this video due to a demand from our more visual learners. Big Mountain Drugs prides itself on its exceptional customer care,” says their marketing manager.

The video shows the ordering process in detail; from a patient’s search for their correct medication, step by step instructions for their online ordering service, and through to check out and delivery. The video starts at the home page, showing how a customer would search on the Big Mountain Drugs website to find their doctor-prescribed medication. After finding their medication, the customer is shown how to add the product to the “cart,” meanwhile verifying the dosage and amounts. From the cart, the customer will be prompted to either log in as a returning customer, or to create a new username and password for themselves. After logging themselves in, the customer is prompted to pay for their prescription. Big Mountain Drugs accepts Visa, Mastercard, certified checks and money orders. After payment has been completed, the customer may enter their address, and expect a prompt delivery right to their home. Big Mountain Drugs our goal is to make customers ordering online process fastest and easiest.

Big Mountain Drugs, an online pharmacy based out of Vancouver, British Columbia, offers certified Canadian pharmacy care at lowered prices. Their mission is to provide safe and reliable medications to their customers. Big Mountain Drugs offers well-known brand-name and generic medications such as generic Lipitor, Motilium, Viagra, Advair and Accutane. The Canadian online pharmacy also offers discounted veterinary prescriptions, enabling their customers to buy Frontline and Advantage for their pets. Big Mountain Drugs specializes in speedy, secure prescription deliveries right to you. They accept prescription and over the counter orders through fax, online orders, and over the phone. The Canadian online pharmacy is proud to offer their telephone service in six languages. Big Mountain Drugs is certified by PharmacyChecker.com, and is a member of the Canadian International Pharmacy Association (CIPA).

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For the original version on PRWeb visit:
http://www.prweb.com/releases/Canadianpharmacy/onlineorderingprocess/prweb9038802.htm

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Popular Birth Control Pills Link to High Risk of Blood Clot

Thursday, December 8th, 2011

from renewleeds

Two older brands “Yaz” and “Yasmin” were found to increase the risk of blood clots, said by Health Canada. It’s heartbreaking when this happens while it’s rare.

Both Yaz and Yasmin sold by Bayer are the best-selling birth control products with benefits; especially it is the # choice for women who are suffering from PSMS and Acne. But now, several different research found that Yaz have higher blood clotting risk than other birth control pills.

Bayer maintains that Yaz is safe. “Based on a thorough assessment of the available scientific data, Bayer believes that its drospirenone-containing products are safe and effective and have a favorable benefit-risk profile when used in accordance with U.S. product labeling”, spokeswoman Rose Talarico told ABC news.

All birth control pills may pose a risk of blood clots. Most birth control drugs combine two female hormones, estrogen and progestin, which help ovulation and sperm. Estrogen along does not cause blood clots, but it has several-folder increased risk of developing bloods. Also the clots can be caused by other factors such as age, family history, obesity or smoking.

The FDA advisory panel will review the studies of the risk of clots associated with the oral contraceptive on Dec 08. Also the FDA will have further investigations on newer birth control drugs.

Big Mountain Pharmacy advises women should discuss the risks and benefits of birth control pills with doctors before they buy Yaz or buy Yasmin, especially drospirenone-containing oral contraceptives.

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Obama Declares: “An Aids-Free Generation in our Near Future”

Friday, December 2nd, 2011

from UNHCR

U.S. President Barack Obama spoke out Thursday, December 1, for this year’s World AIDS Day, declaring the “beginning of the end of AIDS”, thus renewing America’s commitment to defeat the pandemic that has killed over 30 million people.

In support of his statement Obama declared that the US would be upping their budget allocated for AIDS by $50 million and set a goal of providing antiviral drugs to 2 million people within 2 years. Obama gave hope to his citizens saying, “Who could imagine we would be talking about an AIDS-free generation, because that’s what we are talking about.”

According to the United Nations, over the past decade HIV infections have fell and treatments have risen New infections dropped more than a quarter between 2001 and 2009 across 33 countries, with more than 6.6 million receiving antiretroviral therapy in low and middle-income countries last year compared with just 400, 000 in 2003.

The UN secretary general was quoted stating, “Heading into the fourth decade of AIDS, we are finally in a position to end the epidemic”.

For some this seems just too good to be true; after so many years of suffering and so many lives taken too early, thinking of an actual end to the AIDS epidemic is more pf a dream than an actual reality. But the World Health Organization declared “The tide is turning – the tools to achieve an AIDS-free generation are in out hands”.

The only thing that may threaten this amazing goal and forethought is the looming recession; But officials are still increasing HIV research spending, which comes as a relief to the some 34 million people in this world that are currently living with the HIV/AIDS virus. Globally about half of eligible adults are receiving treatment for AIDS with the most dramatic improvement made in the sub-Saharan Africa, which recorded a 20-per-cent jump in people undergoing treatment between 2009 and 2010.

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