Archive for the ‘Colchicine’ Category

Colchicine for Cancer Treatment

Friday, February 3rd, 2012

The University of Bradford’s Institute of Cancer Therapeutics is developing a new drug designed to target only diseased cancerous cells. One of the main ingredients in the team’s experimental drug is colchicine, which is commonly used to treat gout. Although colchicine is a natural ingredient often derived from the Autumn Crocus, the scientists are creating a chemically matched substitute in a laboratory.

This new form of colchicine was created as a first attempt to remove the existing blood supply to a tumor. Without a blood supply to sustain its cell reproduction, the tumor should die off. Scientists have tailored the drug to specifically target an enzyme only found in diseased tissue. this means the drug will also be able to target secondary tumor cells.

According to the lead researcher on the team, this drug will be particularly powerful as it should be able to safely work alongside the patients’ chemotherapy treatments or hormone therapies such as Femara or Arimidex.

For more information see the original release here.

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What You Need to Know About Gout Medication

Friday, July 22nd, 2011

about gout medication

“Not only is gout is one of the most painful types of arthritis, it can disfigure and damage joints if left untreated. Here’s what you need to know to make sure you are taking the best gout medications.”

Gout medication falls into two categories – drugs to relieve the pain and inflammation of an attack, and preventive gout medicine to ward off future attacks and avoid complications.
(more…)

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FDA Colchicine Review Provides Helpful Information

Monday, July 18th, 2011

In the public uproar over the massive increase in the price of the gout medication colchicine following the FDA-ordered removal of generic versions of the gout drug from the American market, many have lost sight of two significant FDA findings.

Concerned that older drugs that have been in use since before the inception of a stringent approval process in the 1960′s may not meet current standards for safety, effectiveness, quality and labeling, the FDA launched the Unapproved Drug Initiative in 2006.

Pharmaceutical companies manufacturing older, unapproved medications were expected to put them through expensive clinical trials to win formal FDA approval. In return, the companies would be given exclusive market rights for a specified time period to allow them to recoup their investment.
(more…)

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Big Mountain Drugs Helps Victims of Shocking Gout Drug Price Hike

Tuesday, July 5th, 2011

Colchicine

After URL Pharma won the exclusive rights to market the gout medication colchicine, over twenty other American pharmaceutical companies were ordered to stop manufacturing it. The price soared from nine cents a pill to almost $5, and Canadian pharmacies rushed to persuade American gout sufferers to buy colchicine from Canada.

Concerned that older drugs that have been in use since before the inception of a stringent approval process in the 1960′s may not meet current standards for safety, effectiveness, quality and labeling, the Food and Drug Administration (FDA) launched the Unapproved Drug Initiative in 2006.

Under this initiative, the consumer protection agency ordered pharmaceutical companies manufacturing unapproved drugs to either undergo rigorous and expensive clinical trials to obtain approval for the drugs, or to remove them from the market. In return, those companies winning approval would be given exclusive market rights for a time period, to allow them to recoup their investment.
(more…)

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Why are Gout Sufferers Paying So Much More for Colchicine?

Friday, July 1st, 2011

Gout pain relief

When the American pharmaceutical company URL Pharma acquired the exclusive rights to manufacture a common gout drug that numerous other companies had been making for years, the price soared from 10¢ a pill to $5 a pill. What’s going on here?

Prescription colchicine is a pain reliever and anti-inflammatory derived from a crocus plant that has been in use since the 1800s. It’s primarily prescribed to treat gout, a painful form of arthritis, but is also an effective treatment for familial Mediterranean fever.

Over twenty different US pharmaceutical companies were manufacturing generic colchicine up until 2010. That’s when the FDA ordered them to stop manufacturing the gout drug within 45 days, and to stop shipping it within 90 days.
(more…)

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Colchicine Effectively Cures FMF and Gout

Monday, March 14th, 2011

When gout is likely to affect 1% or the entire Western population, a drug like Colchicine becomes very useful in suppressing severe inflammation caused by it. The exact effect may not be known, but it reduces uric acid crystallization thereby effectively bringing down the inflammation.

Approximately 5 million US citizens already suffer from gout. In acute conditions, people suffer from frequent attacks of acute inflammatory arthritis where the joints get tender and swell up. High uric acid levels in the blood crystallize and form deposits mainly in the joints. Canada drugs provide a cheap and effective solution to reverse the condition. (more…)

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