Opsumit (Macitentan) is a medication used to treat pulmonary arterial hypertension (high blood pressure in your lungs). Opsumit works by blocking endothelin, a substance that causes the blood vessels in your lungs to narrow, which restricts blood flow and puts strain on the heart. By blocking excessive production of endothelin, Opsumit helps open these blood vessels and improve pulmonary function. This medication improves your ability to exercise, improve some of your symptoms, and help slow down the progression of your disease. Take this medication as directed. Do not use Opsumit if you are pregnant as it can cause harm to the unborn baby. While using Opsumit, you will need regular pregnancy tests, and you must use appropriate birth control. To make sure Opsumit is right for you, tell your doctor if you have ever had liver disease, heart disease, or anemia. Call your doctor immediately if you experience signs of liver problems, or new lung problems. If you experience any serious side effects or signs of an allergic reaction, seek emergency medical attention.
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