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Brand Ditide 50 mg/25 mg from India by GSK

The brand Ditide 50 mg/25 mg comes from India manufactured by GSK. It is available in the quantity of 100 tablets.

Ditide (Triamterene and Benzthiazide) Information

Ditide is a combination medication containing two active ingredients: triamterene (a potassium-sparing diuretic) and benzthiazide (a thiazide diuretic). It is indicated for the treatment of edema (swelling) and hypertension (high blood pressure) in patients for whom combination therapy is appropriate. This fixed-dose combination is typically used when the goal is to enhance the diuretic and antihypertensive effects while minimizing the risk of potassium loss (hypokalemia) often associated with thiazide diuretics alone. Ditide is administered orally, typically once or twice daily.

The mechanism of action involves the synergistic effects of the two components: Benzthiazide is a thiazide diuretic that works in the distal convoluted tubules of the kidney. It inhibits the reabsorption of sodium and chloride, leading to increased excretion of salt and water, and a resulting reduction in blood volume and blood pressure. Triamterene is a potassium-sparing diuretic that works in the collecting ducts of the kidney. It directly blocks the epithelial sodium channels, inhibiting sodium reabsorption and thereby increasing sodium and water excretion. Crucially, this mechanism results in potassium retention, counteracting the potassium loss caused by benzthiazide. By combining these two mechanisms, Ditide provides adequate diuresis and blood pressure reduction while maintaining a more favourable potassium balance.

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Do I need a prescription to order Ditide 50 mg/25 mg ?

Yes, a prescription is required from your physician to order Ditide 50 mg/25 mg.