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Brand Exforge10 mg/160 mg for Hypertension

The brand Exforge 10 mg/160 mg comes from Turkey manufactured by Novartis. It is available in the quantity of 84 tablets.

Exforge (Valsartan and Amlodipine) Information

Exforge is a combination medication containing two active ingredients: valsartan (an Angiotensin II Receptor Blocker or ARB) and amlodipine (a Dihydropyridine Calcium Channel Blocker or CCB). It is indicated for the treatment of hypertension (high blood pressure) in patients for whom combination therapy is appropriate. This fixed-dose combination is typically used when blood pressure is not adequately controlled with either component alone. Exforge is administered orally, typically once daily.

The mechanism of action involves the synergistic effects of the two components: Valsartan blocks the binding of Angiotensin II to the AT1 receptor. This inhibits vasoconstriction and aldosterone release, promoting vasodilation (widening of blood vessels) and the excretion of sodium and water, thus reducing systemic vascular resistance. Amlodipine is a CCB that inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. This causes peripheral arterial vasodilation and a subsequent reduction in peripheral vascular resistance. By combining these two mechanisms, Exforge provides a potent and comprehensive decrease in blood pressure by addressing both the renin-angiotensin system and peripheral vascular tone, often resulting in a superior antihypertensive effect compared to either drug alone.

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Do I need a prescription to order Exforge 10 mg/160 mg ?

Yes, a prescription is required from your physician to order Exforge 10 mg/160 mg.