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Jublia 10 %/8 ml Solution from Canada

Brand Jublia comes from Canada manufactured by Bausch Health. It is available in 8ml of 10% bottle of topical solution. We are supplying in the quantity of 1 and two bottles.

Jublia (Efinaconazole) Information

Jublia (efinaconazole) is a synthetic triazole derivative used as a topical antifungal solution. It is specifically indicated for the treatment of onychomycosis (fungal nail infection) of the toenails caused by the dermatophyte Trichophyton rubrum and Trichophyton mentagrophytes. Unlike traditional nail lacquers, Jublia is a solution that is designed to be easily applied to the entire toenail surface, including the cuticles and the skin folds around the nail. It is typically used once daily for 48 weeks (nearly a year). Because toenails grow very slowly, and the fungus is deeply embedded, an extended treatment duration is necessary to ensure the new nail growth is entirely free of infection. Due to its unique chemical properties, efinaconazole has a high permeation rate through the nail plate, allowing it to reach the site of infection in the nail bed.

The mechanism of action for efinaconazole is fungicidal (killing) and relies on disrupting the fungal cell's structure. Similar to other azole antifungals, efinaconazole works by inhibiting the enzyme lanosterol 14-alpha-demethylase (or CYP51). This enzyme is crucial for synthesizing ergosterol, the primary fatty substance required for the structural integrity of the fungal cell membrane. By inhibiting this key enzyme, efinaconazole prevents the production of ergosterol, leading to the accumulation of toxic intermediate sterols within the cell. This severely impairs the function and stability of the fungal cell membrane, ultimately leading to cell death. Because Jublia is applied topically, it achieves high concentrations within the nail and nail bed while having minimal systemic absorption.

If you have any questions about placing your order, contact us at our toll-free service at 1.877.223.9977. Our dedicated toll-free customer service representative will help provide support from Monday to Friday 5:30am to 6:00pm and weekends Saturday/Sunday 7:00am to 3:30pm (PST).

Do I need a prescription to order Jublia 10 %/8 ml ?

Yes, a prescription is required from your physician to order Jublia 10 %/8 ml.