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Home > Drug Category > Pet Medication > Apoquel and Equivalent

Apoquel Information

Apoquel (Oclacitinib) is used to control itching associated with allergic dermatitis from fleas, food, or contact allergens in dogs. It provides rapid relief, often starting to relieve the itch within 4 hours. Janus Kinase (JAK) inhibitors like Oclactinib selectively inhibit Janus Kinase (JAK) enzymes, particularly JAK1, which play a central role in the signaling of cytokines involved in itch and inflammation. By blocking these signals, Apoquel rapidly reduces itching and inflammation associated with allergic skin conditions.

Apoquel Side Effects

The most common side effects of Apoquel may include vomiting, diarrhea, lethargy, increased thirst, and appetite loss. Call your veterinarian right away if you have any of the serious side effects, such as:
• Respiratory infections;
• Signs of an allergic reaction, such as severe vomiting, difficulty breathing, or facial swelling;
• Skin infections

Apoquel Precautions

Do not use Apoquel if your pet is allergic to Oclactinib or other ingredients in this medication. Before you start administering this medication, tell your veterinarian about your dog’s medical history, including if it has serious infections, immunosuppression, is pregnant or breeding, or is lactating. Tell your veterinarian about all your dog’s medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Apoquel and other medications, such as antibiotics, corticosteroids, cyclosporine, and antiparasitic agents. The safety and effectiveness of Apoquel in pregnant, breeding, or lactating dogs have not been established. Do not administer this medicine to your pet without talking to your veterinarian. Use this medicine exactly as prescribed by your veterinarian. Apoquel comes as tablets and chewable tablets. Administer this medicine orally with or without food. Avoid ingestion, inhalation, or direct contact with your skin or eyes. Pregnant or nursing women should avoid handling Apoquel tablets. Wash your hands thoroughly after administering the drug to your dog. Dogs on long-term Apoquel therapy should have regular blood work to monitor immune and liver function. Always inform your vet if your dog develops new lumps, infections, or unusual fatigue during treatment. Store Apoquel at room temperature, away from moisture and heat. Keep all medicines out of reach of children.

Do I need a prescription to order Apoquel?

Yes, a prescription is required from your physician to order Apoquel.