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Astelin Nasal Spray Information

Astelin Nasal Spray (azelastine hydrochloride) is a prescription nasal spray used to relieve the symptoms of seasonal and perennial allergic rhinitis. It is a unique medication as it is a nasal antihistamine with mast cell stabilizing properties. While many people use oral antihistamines or intranasal corticosteroids for their allergies, Astelin offers a different approach by providing localized antihistamine action directly to the nasal passages. It is highly effective in relieving symptoms such as sneezing, a runny nose, and nasal itching. Unlike some intranasal corticosteroids, which can take several days to reach their full effect, azelastine works relatively quickly, with symptom relief often occurring within minutes.

The mechanism of action for azelastine is twofold. First, it is a potent and selective antagonist of the histamine H1 receptor. Blocking these receptors prevents histamine, a key chemical released during an allergic reaction, from triggering the inflammatory response that causes allergy symptoms. Second, it has a mast cell-stabilizing effect. Mast cells are a type of immune cell that releases inflammatory chemicals like histamine. By stabilizing these cells, azelastine helps to prevent the initial release of these substances, thereby addressing the allergic reaction at an earlier stage. This dual-action mechanism makes it particularly effective for the rapid relief of a wide range of nasal allergy symptoms.

Astelin Nasal Spray is a prescription medication in Canada for adults and children 5 years of age and older. For seasonal allergic rhinitis, the recommended dose is two sprays into each nostril twice daily. For perennial allergic rhinitis, the recommended dose for adults and adolescents 12 years of age and older is two sprays per nostril twice daily. For children ages 5 to 11, the dose is typically one spray per nostril twice daily. It is essential to prime the pump before the first use and after any period of non-use to ensure a full dose is delivered.

Astelin Nasal Spray Side Effects

While Astelin is generally well-tolerated, it can cause some side effects, which are often mild and localized to the nasal area. The most common side effect reported is a bitter taste in the mouth, which can be particularly noticeable after administration. Other common side effects include a headache, drowsiness, nosebleeds, and nasal irritation. Due to the potential for drowsiness, it is crucial to exercise caution when driving or operating heavy machinery until you know how the medication affects you.

However, more serious side effects can occur, although they are rare. If you experience any of the following, you should stop using the medication and seek immediate medical attention:

• Significant Drowsiness and Central Nervous System Depression: While drowsiness is a common side effect, in some individuals, it can be severe and incapacitating. This is particularly concerning when combined with other central nervous system depressants.

• Hypersensitivity Reactions: Though rare, a severe allergic reaction to azelastine is possible. Symptoms of a severe allergic reaction may include a rash, hives, swelling of the face, lips, or tongue, and difficulty breathing.

• Worsening of Asthma: For patients with pre-existing asthma, there have been rare reports of the medication potentially worsening asthma symptoms. Any sudden or significant deterioration of asthma should be considered a profound side effect.

Astelin Nasal Spray Precautions

Before using Astelin Nasal Spray, it is essential to have a thorough discussion with your healthcare provider about your medical history and any other medications you are taking. Astelin should be used with caution in individuals with a history of seizures, as well as those with kidney or liver impairment. It is important to note that the product is contraindicated in patients with a known hypersensitivity to azelastine. Due to the potential for drowsiness, it is crucial to avoid alcohol and other central nervous system depressants, such as sedatives or tranquillizers, as they can significantly increase the sedative effects. You should also not operate heavy machinery or drive a car until you know how the medication affects you. If your symptoms do not improve after a few weeks of use, or if they worsen, you should consult your doctor. For pregnant or breastfeeding individuals, it is essential to consult a healthcare professional before using this product. Additionally, avoid spraying the medication into the eyes, as it can cause irritation and blurred vision.

Shake this nasal spray bottle gently and prime the spray before first use. Spray the prescribed number of sprays into each nostril, usually once or twice daily, as directed by your doctor. Avoid spraying directly onto the nasal septum and try not to sniff deeply to reduce the bitter taste that may come after use. Check out the leaflet in the medication pack for more usage instructions. Store this medication in an upright position at room temperature, keeping it away from sunlight, moisture, and out of children's reach.

Do I need a prescription to order Astelin Nasal Spray?

Yes, a prescription is required from your physician to order Astelin Nasal Spray.