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Home > Drug Category > Menopausal Hormone Therapy > Bijuva and Equivalent

Bijuva Information

Bijuva (Estradiol Hemihydrate/Progesterone) is used to reduce moderate to severe hot flashes caused by menopause. A hot flash is a sudden feeling of warmth in the upper body. It is intense mainly over the face, neck, and chest. Hot flashes are symptoms of menopause and are caused by the body making less estrogen. Estrogens like Estradiol hemihydrate help the body produce more estrogen to reduce hot flashes. Progestins like Progesterone help to reduce the risk of cancer of the uterus, which can be caused by using estrogen. Bijuva is for use only in women who have not had their uteruses removed.

Bijuva Side Effects

The most common side effects of Bijuva may include breast tenderness; headache; vaginal bleeding; pelvic pain; Call your doctor right away if you have any of the serious side effects, such as:
• Breast lumps;
• Rapid weight gain;
• Signs of a blood clot such as sudden vision loss, shortness of breath, coughing up blood;
• Unusual vaginal bleeding

Bijuva Precautions

Do not use Bijuva if you are allergic to Estradiol Hemihydrate, Progesterone, or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have unusual vaginal bleeding; have liver disease; have a history of hormone-related cancer; have gallbladder disease; have hormone-related cancer; have migraines; have lupus; have endometriosis; think you may be pregnant or plan to become pregnant; are breastfeeding, or are planning to breastfeed. Tell your doctor about all the medications you take, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Bijuva and other medications, like clindamycin; levothyroxine; fioricet; Do not use Bijuva if you are pregnant or planning to become pregnant without informing your doctor. This drug is not for use in pregnant women. Do not use Bijuva while breastfeeding without talking to your doctor. The drug is not for use in women who are breastfeeding. This drug is not for use in children. Use your medicine exactly as prescribed by your doctor. Take this drug with food. If you need major surgery or will be on long-term bed rest, you may need to stop using this medicine for a short time. Avoid smoking when using Bijuva. Smoking increases your risk of blood clots and stroke. Avoid consuming grapefruit products while using Bijuva. Grapefruit can cause unwanted side effects. Store this medication at room temperature and keep it out of the reach of children.

Do I need a prescription to order Bijuva?

Yes, a prescription is required from your physician to order Bijuva.