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Home > Drug Category > Skin Medications (Topical/Oral) > Diprosalic and Equivalent

Diprosalic Information

Diprosalic (betamethasone dipropionate and salicylic acid) is a topical medication designed to treat specific skin conditions that are responsive to corticosteroids, especially those characterized by a significant hyperkeratotic, dry, or scaly component. This combination product is highly effective for conditions like psoriasis and chronic eczema. It contains two key active ingredients that work synergistically. Betamethasone dipropionate is a potent corticosteroid that works by suppressing the body's inflammatory response, thereby reducing inflammation, redness, and itching. The second active ingredient, salicylic acid, is a keratolytic agent. Its role is to help soften and break down the thick, scaly outer layer of the skin. This action not only helps to remove the scales and crusts associated with these conditions physically but also facilitates the deeper penetration of betamethasone, allowing the corticosteroid to act more effectively on the inflamed skin beneath. The dual action of Diprosalic provides a comprehensive approach to managing the symptoms of these complex skin conditions.

Diprosalic Side Effects

The most common side effects of Diprosalic are generally localized to the site of application. Patients may experience sensations such as burning, itching, irritation, or dryness. These effects are often temporary and can be managed by adjusting the frequency of application or using a moisturizer. You may also experience folliculitis (inflamed hair follicles) or acne-like breakouts. However, because of the potent corticosteroid and salicylic acid components, there is an increased risk of more serious side effects, particularly with improper use. You should contact your doctor immediately if you experience any of the serious side effects listed below:
• Skin changes: Long-term use of the corticosteroid component can lead to thinning of skin, a condition known as skin atrophy. This can result in increased susceptibility to easy bruising, the development of stretch marks (striae), spider veins (telangiectasias), or a noticeable softening and fragility of the skin. The risk of these effects is particularly high with long-term application on sensitive areas such as the face and groin, or when the medication is applied under occlusive dressings that enhance its absorption. You may also experience hypopigmentation (lightening of the skin).
• Systemic absorption: Prolonged use, application to large areas of the body, or use on broken or inflamed skin can lead to systemic absorption of both active ingredients. The absorption of betamethasone can result in systemic effects such as adrenal suppression, Cushing's syndrome, or hyperglycemia (high blood sugar). The absorption of salicylic acid can lead to a condition known as salicylism, particularly in children. Symptoms of salicylism may include ringing in the ears (tinnitus), dizziness, or vomiting.
• Ophthalmologic effects: If Diprosalic is applied to the skin near the eyes, there is a risk of systemic absorption, which may lead to increased intraocular pressure and potentially cause glaucoma or cataracts.
• Skin infections: The immunosuppressive properties of topical corticosteroids may mask the signs of an underlying skin infection or, in some cases, even worsen it.

Diprosalic Precautions

To ensure the safe and effective use of Diprosalic, it is crucial to follow all precautions. Do not use this medication if you are allergic to betamethasone dipropionate, salicylic acid, or any of the product's other ingredients. Diprosalic is for external use only. Avoid contact with the eyes, mouth, and other mucous membranes. Avoid using on facial rosacea, perioral dermatitis, and skin conditions caused by viruses (e.g., herpes simplex), as the corticosteroid can worsen these conditions. The medication should not be used on children under 12 years of age, for prolonged periods, or on large areas of the body due to the increased risk of systemic absorption of salicylic acid. Use with caution in patients with a history of liver or kidney disease, as these conditions may impair the body's ability to process the absorbed medication. It is essential to inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter products, and any herbal supplements. Diprosalic can interact with other topical medications containing corticosteroids or salicylic acid. To avoid excessive absorption and potential toxicity, it should not be used concurrently with other products that contain salicylic acid.

If you are pregnant or planning to become pregnant, you should discuss the use of Diprosalic with your doctor. It is classified as Pregnancy Category C, and there are no adequate and well-controlled studies in pregnant women. Therefore, it should be used during pregnancy only if the potential benefits outweigh the possible risks to the fetus. Additionally, inform your doctor if you are breastfeeding. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk.

Do I need a prescription to order Diprosalic?

Yes, a prescription is required from your physician to order Diprosalic.