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Home > Drug Category > Menopausal Hormone Therapy > Evorel and Equivalent

Evorel Information

Evorel (Estradiol) is used to ease symptoms of menopause. Menopause occurs when the level of hormones the ovaries produce goes down. This can cause symptoms such as hot flashes, mood swings, and vaginal dryness. Evorel is also used to prevent osteoporosis in some women after menopause. The active ingredient in Evorel is Estradiol. Hormone replacement therapy (HRT), like Estradiol, replaces the estrogen that is normally released by the ovaries. However, in women who still have a womb, estrogen may cause the lining of the womb to build up and get thicker. You may need to add a progestogen hormone to the estrogen.

Evorel Side Effects

The most common side effects of Evorel may include irritated, itchy, or red skin at the application site, breast pain, headache, dizziness, weight gain, diarrhea, and stomach pain. Call your doctor right away if you have any of the serious side effects, such as:
• Convulsions;
• Increased blood pressure;
• Signs of an allergic reaction, such as rash, breathing difficulties, itching or swelling of the face, tongue, or throat;
• Signs of blood clots in the legs or lungs

Evorel Precautions

Do not use Evorel if you are allergic to Estradiol or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have A history of breast cancer, Unexplained vaginal bleeding, Blood clotting disorder, Liver disease, Porphyria, Diabetes, Gallstones, Asthma, Epilepsy, think you may be pregnant, or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Evorel and other medications, such as phenobarbital, rifampicin, efavirenz, St. John’s wort, ritonavir, etc. Do not use Evorel if you are pregnant or planning to become pregnant without informing your doctor. This drug is for use in postmenopausal women. Using this medicine in pregnancy may affect your baby. If you become pregnant while using Evorel, remove it and contact your doctor immediately. Do not use Evorel while breastfeeding without talking to your doctor. Estradiol passes into breast milk and may reduce breast milk production. Use your medicine exactly as prescribed by your doctor.

Evorel comes in skin patches. Apply the patch to clean, dry, cool skin as soon as you open the protective pouch. Stick the patch to a hairless area of the skin below your waist. Do not apply on or near the breasts. Avoid using cream, moisturizer, or talc on the area before applying the patch. Do not use it on irritated skin. Change your patch twice a week to give your body a steady supply of hormones. Change the patch on the same two days every week. This means one patch for three days and the next patch for four days. Do not apply the patch on the same skin area twice in a row. Visit your doctor for regular breast screening and cervical smear tests. Regularly check your breasts for any changes, such as dimpling of skin, lumps, or changes in the nipple. Evorel is not a contraceptive. It would not help to prevent pregnancy. Use non-hormonal contraceptive methods while using this drug until your periods stop completely. Store this medication in its original pouch at room temperature, away from moisture and heat. Keep it out of the reach of children.

Do I need a prescription to order Evorel?

Yes, a prescription is required from your physician to order Evorel.