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Latuda (Lurasidone) Information

Latuda, which contains the active ingredient lurasidone, is an atypical antipsychotic used for the treatment of schizophrenia in adults and adolescents aged 13–17 years, and for depressive episodes associated with bipolar I disorder in adults (as monotherapy or adjunct therapy with mood stabilizers). It helps reduce hallucinations, delusions, disorganized thinking, and mood swings, improving clarity of thought and daily functioning. Latuda is taken by mouth once daily with food and is available as film-coated tablets. The drug is taken once daily and is well-tolerated, making it suitable for long-term therapy.

The mechanism of action of lurasidone involves selectively blocking certain dopamine and serotonin receptors in the brain, helping restore balance to the neurotransmitter systems responsible for mood, perception, and behavior. By blocking dopamine D2 receptors, latuda reduces psychotic symptoms such as hallucinations and delusions. Blocking serotonin 5-HT2A receptors further improves mood and cognition. Lurasidone also interacts with other serotonin receptors, which can help stabilize mood and reduce agitation.

Latuda Side Effects

Latuda is generally well-tolerated, but common side effects may occur. Commonly reported effects include drowsiness or sleepiness, nausea or vomiting, restlessness or an inability to sit still (akathisia), indigestion or stomach discomfort, and mild weight gain. Some individuals may also experience mild dizziness, sleep difficulties, fatigue, or weakness. Adolescents may be more likely to notice increased restlessness or agitation when starting treatment.

More serious side effects can occur, leading to significant monitoring protocols. If you experience any of the following symptoms, stop taking the medication and seek immediate medical attention:
• Abnormal heart rhythm: palpitations, fainting, or chest discomfort
• High blood sugar or metabolic changes: excessive thirst, frequent urination, confusion
• Neuroleptic Malignant Syndrome (NMS): high fever, muscle stiffness, confusion, sweating, fast heartbeat
• Seizures
• Severe allergic reactions: swelling of the face, lips, or throat, difficulty breathing, rash
• Severe low blood pressure: dizziness, fainting, or collapse
• Sudden mood changes or suicidal thoughts, particularly during treatment initiation or dose adjustments
• Tardive Dyskinesia (TD): involuntary movements of the face, tongue, or limbs

Latuda Precautions

Do not use latuda if you are allergic to lurasidone or any ingredient in the formulation. Before starting treatment, inform your doctor about your complete medical history. People with diabetes, heart disease, low blood pressure, a history of stroke, seizures, movement disorders, or liver or kidney problems may require careful monitoring and dose adjustment. Latuda can cause mild to moderate metabolic changes, so periodic checks of blood sugar, weight, and cholesterol may be recommended. Tell your doctor about all medications you are taking, including prescription drugs, over-the-counter products, herbal supplements, and vitamins. Lurasidone is metabolized by the liver enzyme CYP3A4. Strong inhibitors or inducers of this enzyme may require dose adjustments. Avoid alcohol because it can increase drowsiness and impair judgment.

Inform your doctor if you are pregnant or planning to become pregnant. Using latuda during the last trimester may affect the newborn, leading to complications such as breathing difficulties or feeding problems. If you are breastfeeding, consult your doctor because lurasidone may pass into breast milk.

Take latuda exactly as prescribed by your doctor, usually once daily with food to ensure proper absorption. Do not crush, chew, or split tablets unless your doctor instructs otherwise. Consistency in timing helps maintain steady levels in your system. Do not stop taking latuda suddenly without consulting your doctor, as abrupt discontinuation may lead to recurrence of symptoms or withdrawal effects. Store latuda tablets at room temperature, away from moisture, heat, and direct light, and keep them out of reach of children.

Do I need a prescription to order Latuda?

Yes, a prescription is required from your physician to order Latuda.