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Home > Drug Category > Parkinson's Disease Medication > Madopar and Equivalent

BigMountainDrugs.com supplies only genuine Madopar from the UK shipped using the UK packaging. This Madopar is manufactured by Genetech Inc. (a member of Roche Group), the worldwide manufacturer of Madopar. This offer is neither endorsed nor authorized by Genetech Inc. (the United States and Canadian distributor of Madopar). BigMountainDrugs.com has no affiliation whatsoever with Genetech Inc.

Madopar Information

Madopar (Levodopa/Benserazide) is primarily used to treat the symptoms of Parkinson's disease. Parkinson's disease is a neurological condition with symptoms like tremor, stiffness, and slow movement, which are generally attributed to a deficiency of a critical chemical in the brain called dopamine. The effectiveness of this medication lies in the synergistic effect of its active components: levodopa and benserazide.

Levodopa is the primary active component. Once ingested, it is converted into dopamine by the brain. It's a precursor to the dopamine that the brain needs. Benserazide is known as a decarboxylase inhibitor. It basically prevents the levodopa from being broken down into dopamine before it reaches the brain. By protecting levodopa in the bloodstream, more of it can cross the blood-brain barrier, which means a smaller dose is needed and some associated peripheral side effects of dopamine are reduced. While Madopar can significantly improve movement symptoms associated with Parkinson's, it's important to note that it does not cure Parkinson's disease itself, as it doesn't stop the loss of the dopamine-producing cells.

Madopar can also be used to treat restless leg syndrome. Madopar's action in optimizing dopamine levels helps treat this condition, as restless legs syndrome is believed to be associated with dysfunction in the brain's dopaminergic system. Studies show that the levodopa/benserazide combination can significantly reduce the severity of restless leg syndrome. It even improves sleep quality and enhances quality of life in the short term.

Madopar Side Effects

Like all medications, Madopar appears to have a range of possible side effects.

Common mild side effects of this medication include nausea and vomiting, loss of appetite, weight gain, constipation, tiredness, difficulty in sleeping, hiccups, restlessness, water retention, cramps, dark discoloration of the mouth, tongue, or saliva, loss of taste sensation, and dizziness (especially while getting up from a sitting or lying position). Contact your doctor if these mild side effects persist or worsen.

Stop taking this medicine and contact your doctor immediately if you experience any serious side effects, including the following:
• Allergic reactions such as breathing difficulties, body itching, body rash, skin blistering, swelling of the face, mouth, tongue, lips, or throat;
• Anemia (low red blood cells) with symptoms like dizziness, pale skin, unusual tiredness;
• Gastrointestinal bleeding with symptoms such as black, tarry stools, or vomiting material that looks like coffee grounds;
• Heart problems with symptoms like irregular or abnormal heartbeat, dizziness, fainting, nausea and vomiting, chest pain;
• Low white blood cell count with symptoms such as fever, chills, and other signs of infections of your mouth, gums, throat, and lungs;
• Neurological or mental disorders with symptoms like hallucinations, confusion, uncontrolled movements of the body, depression;
• Unusual behavioral activities such as compulsive or uncontrolled behavior (e.g., gambling, spending), and hallucinations

Inform your doctor about any other side effects you notice that are not listed here.

Madopar Precautions

Do not use this medication if you are allergic to the active and inactive ingredients in Madopar, or any other medicines. Before you start taking this medication, ensure that you inform your doctor about any prior or current medical conditions, including the following:
• Abdominal problems such as peptic ulcer disease;
• Bone problems such as osteomalacia;
• Diabetes;
• Eye conditions such as glaucoma;
• Heart disease, including rhythm abnormalities;
• Kidney problems;
• Liver problems;
• Mental problems such as anxiety disorder, depression;
• Overactive thyroid gland;
• Skin cancer

This medication can cause drowsiness, so avoid driving, operating machinery, or performing other potentially hazardous tasks until you know how it affects you. Inform your doctor if you or those around you observe unusual urges or cravings that lead to behaviors you typically wouldn't engage in. This may include difficulty resisting impulses that could harm yourself or others, such as addictive gambling, excessive eating or spending, heightened sex drive, or increased sexual thoughts. These behaviors are known as impulse control disorders, and your doctor may need to reassess your treatments based on this information. Inform your doctor that you are taking this medication before performing a blood test or undergoing a surgical procedure. This is because you may need to stop taking Madopar before these procedures.

This medication is not suitable for use in pregnant and breastfeeding women. In fact, women of reproductive age are typically advised to use contraception while taking the medicine. If you get pregnant while taking Madopar, talk to your doctor immediately. Madopar is not recommended for use in individuals under 25 years of age, as it may affect normal bone development in this age group. Some medications should not be used along with Madopar due to the risk of severe adverse drug interactions. For example, drugs belonging to the monoamine oxidase inhibitor class are not used while taking Madopar, and within 14 days after stopping Madopar. Therefore, before using this Parkinson's disease medication, inform your doctor about any other medications you are currently taking, including herbal medicines and supplements, to determine if it is safe to use along with Madopar.

Madopar is available as capsules or dispersible tablets to be taken orally as directed by your doctor. The dispersible tablet is meant to be dissolved in a glass of water or orange squash, then stirred gently until completely dissolved. Like regular Madopar capsules, dispersible tablets are often recommended to be taken on an empty stomach, at least 30 minutes before meals. Swallow the Madopar capsule whole with a full glass of water. Do not crush or chew the capsule unless directed otherwise by your doctor. Your doctor will determine the best dose for you based on your medical history. Store this medication at room temperature and keep it out of reach of pets and children.

Do I need a prescription to order Madopar?

Yes, a prescription is required from your physician to order Madopar.