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Home > Drug Category > Diabetic Medications and Products > Nesina and Equivalent

Nesina Information

Nesina (Alogliptin) is used alone or with other medications to control blood sugar in individuals living with type 2 diabetes mellitus. It is typically used along with a healthy diet and lifestyle modifications. Type 2 diabetes is a chronic condition where the body either doesn't produce enough insulin or doesn't effectively use the insulin it produces, leading to high blood sugar levels. Left uncontrolled, high blood sugar can lead to serious health complications over time. The active ingredient, alogliptin, belongs to a class of drugs known as Dipeptidyl Peptidase-4 (DPP-4) inhibitors. Alogliptin inhibits the action of the DPP-4 enzyme, which usually breaks down incretin hormones (like GLP-1 and GIP). By preventing this breakdown, alogliptin increases the levels of active incretin in the body. These incretins stimulate the pancreas to release more insulin when blood sugar levels are high and reduce the amount of sugar produced by the liver, thereby lowering blood glucose.

Nesina Side Effects

Like all medications, alogliptin may cause some side effects. Some common side effects include abdominal pain, muscle aches, flu-like symptoms, constipation, headaches, nausea, and vomiting. Stop taking this medicine and contact your doctor immediately if you experience any serious side effects, including the following:
• Allergic reactions such as breathing difficulties, hives, swelling of the face, lips, or throat;
• Anemia (low red blood cells) with symptoms including dizziness, pale skin, unusual tiredness;
• High blood pressure and cholesterol levels;
• Liver problems with symptoms including nausea, vomiting, yellow eyes and skin;
• Low blood sugar with symptoms such as palpitations, excessive sweating, headache, anxiety and fainting;
• Muscle damage with symptoms such as unexplained muscle pain, tenderness or weakness, or brown or discolored urine;
• Pancreatitis with symptoms such as abdominal pain on the upper left side, back pain, nausea;
• Skin rash and blistering

Inform your doctor about any other side effects you notice that are not listed here.

Nesina Precautions

Do not use this medicine if you are allergic to alogliptin or any other ingredients in Nesina. Before using this medication, ensure you inform your doctor about any medical conditions you previously or currently have, including the following:
• Gallbladder stones;
• Heart disease;
• High blood cholesterol;
• Kidney disease;
• Liver disease;
• Pancreatitis

This medication should not be used to treat Type 1 diabetes or diabetic ketoacidosis (a serious diabetic complication). Before undergoing surgery, inform your healthcare provider that you are taking this medication. Your doctor will monitor your diabetes mellitus with regular blood tests, including checks of your blood sugar levels. Consult your doctor before using this medication during pregnancy or while breastfeeding. Nesina is not recommended for use in children. It should be used with caution in older adults as they are more likely to develop its side effects. Alogliptin may interact with other medications or substances, such as benazepril, captopril, insulin, sulfonylureas, and somatropin. Therefore, inform your healthcare provider about all the medicines, including herbal supplements and over-the-counter medications, that you are taking before starting Nesina to prevent potential drug interactions. Take Nesina tablets orally with or without food. This medication should be swallowed whole and not chewed or crushed. Your doctor will determine the appropriate dose of this medication for you based on your specific condition. Take this medicine regularly as prescribed for optimal effectiveness. Store it in a cool, dry place, and keep it out of the reach of children and pets.

Do I need a prescription to order Nesina?

Yes, a prescription is required from your physician to order Nesina.