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Home > Drug Category > Skin Medications (Topical/Oral) > Nix Skin Product and Equivalent

Nix Information

Nix Skin Product (Permethrin) is a topical skin product used to treat parasitic infestations, specifically head lice and scabies. Head lice are small insects that live on the scalp and feed on human blood, causing intense itching and discomfort. Scabies is a skin condition caused by tiny mites that burrow into the skin, triggering allergic reactions and a severe itchy rash. Both conditions are highly contagious and spread through close contact or the sharing of personal items. The active ingredient in Nix Skin Product is permethrin, a synthetic chemical that belongs to the pyrethroid class of drugs. Permethrin works by disrupting the normal function of parasite nerve cells, leading to paralysis and death of the lice or mites. It also has residual activity, which helps kill any newly hatched parasites and prevent new infestations for up to 14 days if used correctly. These actions make Nix Skin Product effective in breaking the life cycle of the parasite and clearing the infestation. Its safety profile allows safe use in adults and children over 2 months old, making it a widely accessible and effective option for treating these common infestations.

Nix Side Effects

While this skin product is generally safe to use, it can cause mild side effects such as itching, mild burning or stinging, redness, numbness, tingling, or rash. Stop using this topical medicine and contact your doctor immediately if you experience any serious side effects, including the following:
• Allergic reactions such as breathing difficulties, hives, swelling of the face, lips, or throat;
• Skin pain;
• Skin puffiness

Inform your doctor about any other side effects you notice that are not listed here.

Nix Precautions

Do not use this topical medicine if you are allergic to permethrin or any other ingredients in Nix Skin Product. It is worth noting that this medication can exacerbate symptoms of scabies infestation. It does not mean you need to repeat the treatment. Repeat the treatment only if you see live mites or new lesions on your skin, as directed by your doctor. This medication is not recommended for use in children less than 2 months old. Talk to your doctor before using this medication during pregnancy or while breastfeeding. Some drugs, such as corticosteroids, may interact with this topical permethrin and increase the risk of adverse effects. Therefore, inform your healthcare provider about all the medicines, including other topical medications that you are using, before using Nix Skin Product to prevent potential drug interactions.

This medication is available in different forms, specifically for lice and scabies infestations. For head lice, wash your hair, apply the 1% product to saturate the hair and scalp, leave it on for 10 minutes, then rinse and comb out the nits. For scabies, the 5% cream is massaged into all skin surfaces from head to toe, left on for 8-14 hours, and then washed off. Avoid getting this medication in contact with your eyes, nose, and mouth. A single application of this product is usually sufficient to eliminate the infestation. However, the associated itching may take longer to subside completely. Ensure to read the product label for specific instructions and consult your doctor for further details. Store this product at room temperature and keep it out of the reach of children and pets.

Do I need a prescription to order Nix Skin Product?

No, a prescription is not required from your physician to order Nix Skin Product.