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Home > Drug Category > Weight Loss Medications > Orforglipron and Equivalent

Orforglipron Information

Orforglipron (Orforglipron) is an experimental medication being investigated for the treatment of type 2 diabetes and weight loss in people with obesity. Type 2 diabetes is a chronic condition characterized by persistently high blood sugar levels, primarily due to the body's inability to use insulin properly or produce enough of it. This condition, also known as non-insulin-dependent or adult-onset diabetes, affects how the body uses sugar (glucose) for energy. Non-peptide glucagon-like peptide-1 (GLP-1) receptor agonists like Orforglipron bind to and activate the GLP-1 receptor. The receptor is involved in several critical metabolic processes, such as stimulating insulin release, suppressing glucagon secretion, slowing gastric emptying, decreasing appetite and increasing satiety.

Orforglipron Side Effects

The most common side effects of Orforglipron may include constipation, diarrhea, nausea, indigestion, and vomiting. Call your doctor right away if you have any of the serious side effects, such as:
• Signs of an allergic reaction, such as rash, breathing difficulties, itching or swelling of the face, tongue, or throat;
• Signs of gallbladder problems, such as gallstones or inflammation

Orforglipron Precautions

Do not use Orforglipron if you are allergic to Orforglipron or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have a history of medullary thyroid carcinoma (MTC), a history of pancreatitis, severe gastrointestinal disorders, think you may be pregnant, or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Orforglipron and other medications, such as insulin, oral contraceptives, etc. Inform your doctor if you are pregnant or planning to become pregnant before using Orforglipron. It is recommended to avoid using this medicine in pregnancy. Discuss alternative treatments to Orforglipron during pregnancy with your doctor. Inform your doctor if you are breastfeeding or planning to breastfeed before using Orforglipron. It is recommended to avoid using Orforglipron while breastfeeding. Breastfeeding women should discuss safer alternative treatments with their doctor. Do not use this medicine in children without talking to your doctor. The safety and effectiveness of this medicine in children has not been established.

Use your medicine exactly as prescribed by your doctor. Orforglipron comes as a tablet. Swallow the tablet by mouth. Do not crush, chew, or break it. You can take the medicine at any time of the day. Store Orforglipron at room temperature, away from moisture and heat. Keep all medicines out of reach of children.

Do I need a prescription to order Orforglipron?

Yes, a prescription is required from your physician to order Orforglipron.