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Home > Drug Category > Fertility Drugs > Orgalutran and Equivalent

Orgalutran Information

Orgalutran (Ganirelix) is used in fertility treatments to prevent premature ovulation in women undergoing ovarian stimulation. Premature ovulation is the early release of eggs from the ovary, while ovarian stimulation is a process where medications are used to encourage the ovaries to develop multiple mature eggs for fertility procedures. Premature ovulation during fertility treatment can negatively impact outcomes, potentially leading to cycle cancellation or poor-quality eggs that may not fertilize or lead to successful pregnancies. Synthetic gonadotropin-releasing hormone (GnRH) antagonist like Ganirelix works by blocking the action of natural GnRH on the pituitary gland. This leads to the rapid suppression of the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in the pituitary gland.

Orgalutran Side Effects

The most common side effects of Orgalutran may include skin reaction at the injection site, headache, nausea, and abdominal pain. Call your doctor right away if you have any of the serious side effects, such as:
• Signs of an allergic reaction, such as rash, breathing difficulties, itching or swelling of the face, tongue, or throat;
• Signs of ectopic pregnancy, such as abdominal cramping, fainting, shoulder pain, spotting;
• Signs of ovarian hyperstimulation syndrome (OHSS), such as severe pelvic pain, vomiting, significant weight gain, abdominal swelling, etc;
• Vaginal bleeding

Orgalutran Precautions

Do not use Orgalutran if you are allergic to Ganirelix or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have moderate or severe kidney or liver problems, think you may be pregnant, or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Orgalutran and other medications. Inform your doctor if you are pregnant or planning to become pregnant before using Orgalutran. This medicine should not be used once pregnancy is achieved. Inform your doctor if you are breastfeeding or planning to breastfeed before using Orgalutran. It is unknown if Ganirelix passes into breast milk or if it may harm a nursing infant. Do not use this medicine in children without talking to your doctor. Use your medicine exactly as prescribed by your doctor. Orgalutran comes as an injection. Inject your prescribed dose once daily under the skin. Inject the drug under the skin of your upper thigh as directed by your doctor. Your doctor will show you how to use this medication properly. The length of treatment is usually about 5 days but can range from 1 to 19 days. Store Orgalutran at room temperature, away from moisture and heat. Keep all medicines out of reach of children.

Do I need a prescription to order Orgalutran?

Yes, a prescription is required from your physician to order Orgalutran.