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Home > Drug Category > Platelet Aggregation Inhibitors > Plavix and Equivalent

BigMountainDrugs.com supplies only genuine Plavix from Canada and Turkey shipped using Canadian and Turkish packaging. This Plavix is manufactured by Sanofi (SANOFI SA), the worldwide manufacturer of Plavix. This offer is neither endorsed nor authorized by Sanofi (SANOFI SA). BigMountainDrugs.com has no affiliation whatsoever with Sanofi (SANOFI SA).

Plavix (Clopidogrel) Information

Plavix, which contains the active ingredient clopidogrel, is an antiplatelet medication. It is used to reduce the risk of heart attack, stroke, and other clot-related problems in people with atherosclerotic cardiovascular disease. It is often prescribed after a heart attack or ischemic stroke, or for people with peripheral arterial disease. Plavix is also used together with aspirin in patients who have had certain heart procedures, such as stent placement, to help prevent clots from forming inside the stent. It is taken once daily by mouth, making it convenient for long-term protection.

The mechanism of action of clopidogrel involves blocking P2Y12 receptors on platelets. This prevents the platelets from sticking together and forming harmful clots. The effect lasts throughout the platelet's lifespan, so one dose per day is usually enough to maintain steady protection. Because it requires activation by liver enzymes, there may be some variation in response. However, once activated, it helps keep blood flowing smoothly and reduces the risk of future cardiovascular events.

Plavix Side Effects

Plavix is generally well-tolerated, but some common side effects may occur. Common side effects include bruising, nosebleeds, diarrhea, rash, stomach upset, and mild bleeding from cuts that take longer to stop. Some people may experience headaches or heartburn-like discomfort.

More serious side effects can occur, leading to significant monitoring protocols. Seek immediate medical attention for these symptoms, but do not discontinue the medication unless instructed by your doctor:
• Chest pain, shortness of breath, or sudden leg swelling (possible clotting event)
• Fever, unexplained fatigue, or pale skin (possible rare blood disorders such as TTP)
• Signs of severe allergic reactions, including swelling of the face or throat, difficulty breathing, rash
• Signs of severe bleeding, including black or tarry stools, blood in urine, vomiting blood, coughing up blood, or unexplained severe bruising
• Sudden severe headache, confusion, or weakness (possible internal bleeding or stroke)

Plavix Precautions

Do not use Plavix if you are allergic to clopidogrel or any ingredient in the drug. If you have active bleeding, such as a bleeding ulcer or brain hemorrhage, do not use this medicine. Before starting treatment, inform your doctor of your complete medical history, especially if you have a history of stomach ulcers, liver disease, recent surgery, bleeding disorders, or if you bruise easily. Because clopidogrel increases the risk of bleeding, your doctor may monitor you more closely if you have additional risk factors. Tell your doctor about all medications you take, including prescription drugs, over-the-counter products, supplements, and herbal remedies. Plavix can interact with blood thinners (such as warfarin and DOACs), NSAIDs, proton pump inhibitors (such as omeprazole or esomeprazole), certain antidepressants, and medications that affect liver enzymes. Alcohol may increase the risk of stomach bleeding and should be limited.

Inform your doctor if you are pregnant or planning to become pregnant. Antiplatelet therapy may increase bleeding during pregnancy or delivery, so your doctor will help weigh the risks and benefits. It is unknown if clopidogrel passes into breast milk. If you are planning to breastfeed, discuss the benefits and risks of using this medicine with your doctor. Take Plavix exactly as prescribed, typically once daily with or without food. Try to take it at the same time each day to keep its effects consistent. Do not stop Plavix suddenly unless your doctor instructs you to do so. Stopping this medicine suddenly can increase the risk of a heart attack or stent-related clotting. Store Plavix at room temperature, away from heat, moisture, and light, and keep it out of reach of children.

Do I need a prescription to order Plavix?

Yes, a prescription is required from your physician to order Plavix.