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Home > Drug Category > AIDS Medications, HIV Treatments > Trizivir and Equivalent

Trizivir Information

Trizivir (Abacavir/Lamivudine/Zidovudine) belongs to a group of antiretroviral medicines and is used in combination with other antiretrovirals to treat Human Immunodeficiency Virus (HIV) infection. The Human Immunodeficiency Virus (HIV) is a retrovirus (a type of virus). Infection with HIV damages the immune system and can lead to Acquired Immune Deficiency Syndrome (AIDS) and other related illnesses. Trizivir does not cure HIV but helps to prevent further damage to the immune system by slowing down production of new viruses. Trizivir also increases the CD4 cell count in your blood. CD4 cells are a type of white blood cells that are important in helping your body fight infection. You must be sure to be seen regularly by your health care provider. Trizivir is available as 300 mg/150 mg/300 mg tablets.

Trizivir Side Effects

The most common side effects of Trizivir may include nausea, vomiting, stomach pain, diarrhea, loss of appetite; headache; difficultly sleeping; muscle pain and inflammation; fatigue, fever, malaise and lethargy; rash; hair loss. Call your doctor right away if you have any of the serious side effects such as:
• General ill feeling, extreme tiredness, body aches;
• Immune system problems such as signs of a new infection, diarrhea, weight loss;
• Lactic acidosis (unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired);
• Low white blood cell counts (fever, mouth sores, skin sores, sore throat, cough);
• Low red blood cells (pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet);
• Liver problems (swelling around your midsection, right-sided upper stomach pain, loss of appetite, dark urine, clay-colored stools, yellowing of the skin or eyes);
• Swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence;
• Signs of allergic reaction such as skin blisters or peeling, eye redness, swelling in your face or throat, trouble breathing, fever; rash, nausea, vomiting, diarrhea, stomach pain;
• Trouble speaking or swallowing, problems with balance or eye movement, weakness.

Trizivir Precautions

Do not use Trizivir if you are allergic to Abacavir/Lamivudine/Zidovudine or to any other ingredients in this medication or if you have liver disease; have a very low red blood cell count (anemia) or very low white blood cell count. Before you start taking this medication, tell your doctor about your medical history, especially if you have kidney or liver disease (including hepatitis B or C); have low blood cell counts (bone marrow problem); have heart problems, smoke, or have high blood pressure, high cholesterol, or diabetes; are taking interferon or ribavirin; have had previous use of any NRTI class medicine; have been tested and know whether or not you have a gene variation called HLAB*5701; drink alcohol or take medicines that contain alcohol; if you are pregnant, or breastfeeding. If you are pregnant or if you are planning to become pregnant, talk to your doctor about the risks and benefits to you and your baby of taking Trizivir during your pregnancy. Trizivir and similar medicines may cause side effects in unborn babies. Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk. Tell your doctor about all the medications you take including prescription, OTC, herbal supplements and vitamins. There may be a drug interaction between Trizivir and other medications. Trizivir can make you dizzy and have other side effects that make you less alert. Do not drive or operate machines unless you are feeling well.

Do I need a prescription to order Trizivir?

Yes, a prescription is required from your physician to order Trizivir.