Xenazine (Tetrabenazine)

TypeDrug NameDosage 
Xenazine25 mg

Generic Equivalent of Xenazine

TypeDrug NameDosage 
Tetrabenazine25 mg

Xenazine Information:

Xenazine (Tetrabenazine) is medication used to treat the symptoms of hyperkinetic diseases (characterized by uncontrollable movements), specially Huntington’s Disease, Tourette Syndrome, Tardive Dyskinesia, and Hemiballismus. Xenazine is a vesicular monoamine transporter type 2 (VMAT2) that is thought to work through its effect on monoamines. Xenazine is a reversible depletor of dopamine, serotonin, norepinephrine, and histamine, monoamines that come from nerve terminals. Xenazine inhibits vesicular monoamine transporter 2, resulting in a decreased intake of monoamines into synaptic vesicles, as well as a depletion of monoamine storage. As monoamines play a large roll in motor function, the depletion of them can lead to a lessening of uncontrollable movements. You should not use Xenazine if you have severe or untreated depression, suicidal thoughts, liver disease, or if you have taken reserpine in the past 20 days. Tell your doctor about any medications you have used in the past or any medications you are currently using in order to reduce the risk of interactions. Do not use Xenazine if you have used a MAO inhibitor in the past 14 days, as an interaction can occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Take this medication as directed. You may have depression or thoughts about suicide while taking this medication. Report any changes in your mood to your doctor. Common side effects of Xenazine include drowsiness, depressed mood, nausea, or feeling anxious, agitated, or restless. Call your doctor immediately if you experience tremors, shaking, restless movement, problems with balance, uncontrolled muscle movements in your face, trouble swallowing, fast or pounding heartbeats, light-headedness, or symptoms of a severe nervous system reaction including rigid muscles, high fever, sweating, confusion, or fast or uneven heartbeats. If you experience any signs of an allergic reaction or are having serious thoughts of suicide, seek immediate medical attention.

Xenazine Availability

Big Mountain Drug currently offers Xenazine Tablets from Canada (Nitoman) by Valeant (Bausch Health), United Kingdom by Cambridge Laboratories and New Zealand (Motetis) by Douglas, in a dosage of 25 mg tablets. The generic Tetrabenazine is available from Canada and India also called Revocon by Sun Pharma, available in the dosage of 25 mg tablets.

The generic alternative is not manufactured by the company that makes the brand product.

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Prescriptions Dispensed from Canada are Dispensed by: Candrug Pharmacy, ID#18985 604-543-8711. Pharmacy Manager: Sanaa Abdelati. This pharmacy is duly licensed in the province of British Columbia, Canada by the College of Pharmacists of BC. If you have any questions or concerns you can contact the college at: 200-1765 West 8th Ave Vancouver, BC V6J 5C6 Canada.
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