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Home > Drug Category > Psoriasis Medication > Zoryve and Equivalent

Zoryve Information

Zoryve (Roflumilast) is used to treat plaque psoriasis and atopic dermatitis. Plaque psoriasis is a condition that causes itchy, painful rash with red patches of skin. It is an autoimmune condition where the immune system mistakes healthy cells for foreign invaders. Certain medications may also cause the condition. Atopic dermatitis, or eczema, is a chronic skin condition that causes inflammation, redness, and intense itching. Although the exact cause of this skin condition is unknown, it mainly occurs due to a combination of genetics, the immune system, and environmental factors. Zoryve cream is also used to treat seborrheic dermatitis. This chronic condition causes flaky, scaly, greasy skin on the scalp, face, chest, or oily body areas. Phosphodiesterase-4 (PDE4) inhibitors like Roflumilast work by inhibiting the enzyme PDE4, which helps reduce inflammation and improve plaque psoriasis and seborrheic dermatitis symptoms.

Zoryve Side Effects

The most common side effects of Zoryve may include diarrhea, headache, nausea, and pain at the application site. Call your doctor right away if you have any of the serious side effects, such as:
• Signs of an allergic reaction, such as rash, breathing difficulties, itching or swelling of the face, tongue, or throat;
• Signs of liver problems, such as dark urine, pale stools, nausea, appetite loss

Zoryve Precautions

Do not use Zoryve if you are allergic to Roflumilast or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have liver problems, think you may be pregnant, or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Zoryve and other medications, such as oral contraceptives, other topical medications, etc. Do not use Zoryve if you are pregnant or planning to become pregnant without informing your doctor. It is unknown if this medicine will harm an unborn baby. Discuss the benefits and risks of using this drug in pregnancy with your doctor. Do not use Zoryve while breastfeeding without talking to your doctor. It is unknown if Roflumilast passes into breast milk or if it may harm a nursing infant. If you are using this medication on your breast area, use it on the smallest skin area and for the shortest period. Do not apply Zoryve foam or cream directly to your nipple or areola to avoid contact with your baby. The safety and effectiveness of Zoryve cream in children younger than 6 years old have not been established. Do not use Zoryve foam in children below 9 years old.

Use your medicine exactly as prescribed by your doctor. Zoryve comes as a foam and cream. This medication is a topical medication and should be used on the skin only. Please do not take it by mouth. To use this medication, wash your hands before and after applying. Apply a thin layer of Zoryve cream to the affected area once a day. If you use Zoryve foam, shake the can well before each use. Turn the can upside down and press the nozzle to dispense a small amount of foam into your hand. Apply a thin layer of the foam to the affected area as directed by your doctor. Gently rub the medication into the skin until it is fully absorbed. Do not cover the treated area with bandages or tight dressings unless directed by your doctor. Do not use Zoryve cream on your face, groin, or in your vagina unless directed by your doctor. This medication is flammable. Avoid fire, flame, or smoking when applying the medication and right after applying the medication. Store Zoryve at room temperature, away from moisture and heat. Store the can upright. Do not freeze. Keep all medicines out of reach of children.

Do I need a prescription to order Zoryve?

Yes, a prescription is required from your physician to order Zoryve.