Akynzeo (Netupitant/Palonosetron) is anti-emetic medication used to treat nausea and vomiting associated with chemotherapy treatment. The two active substances in Akynzeo, Netupitant and Palonosetron, work by blocking the neurokinin-1 receptors which cause delayed nausea and vomiting after chemotherapy, and by blocking the 5HT3 receptors which cause immediate nausea and vomiting. This medication is often used together with a steroid called dexamethasone. Inform your doctor if you are pregnant or plan to become pregnant, as the medication can harm the fetus. Tell your doctor about any medical conditions, allergies, or medications you are currently taking in order to avoid worsening any conditions. If you experience any symptoms of serotonin syndrome or an allergic reaction, seek immediate medical attention. Take this medication as directed. Talk to a medical professional about any other side effects this medication may cause.
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