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Home > Drug Category > Asthma Medication/ Respiratory Disorders > Wixela Inhub and Equivalent

Wixela Inhub Information

Wixela Inhub (Fluticasone Propionate/Salmeterol) is used to control and prevent symptoms (wheezing and shortness of breath) caused by asthma or ongoing lung disease (chronic obstructive pulmonary disease-COPD, which includes chronic bronchitis and emphysema). It contains 2 medications fluticasone and salmeterol. Fluticasone belongs to a class of drugs known as corticosteroids. It works by reducing the irritation and swelling of the airways. Salmeterol belongs to the class of drugs known as long-acting beta agonists. It works by relaxing the muscles around the airways so that they open up and you can breathe more easily. Wixela Inhub should be used in patients who have asthma that is not adequately controlled with a long-term asthma medication such as an inhaled corticosteroid (ICS) alone; or whose asthma severity requires treatment with both an ICS and long acting beta2 agonist (LABA). Before using this medication, it is important to learn how to use it properly. This medication must be used regularly to be effective. It does not work right away and should not be used to relieve sudden asthma attacks. If an asthma attack occurs, use your quick-relief inhaler as prescribed.

Wixela Inhub Side Effects

The most common side effects of Wixela Inhub may include effects on heart, faster heart beat than usual; pain in joints, muscle cramps; effects on nervous system, feeling a little shaky, headache, behavioral changes (including agitation, anxiety, and irritability), disturbed sleep, fainting, spinning sensation (vertigo), dizziness; hoarseness and voice changes; increased bruising. Call your doctor right away if you have any of the serious side effects such as:
• Chest pain or pressure;
• Change in eyesight, eye pain, or very bad eye irritation;
• Feeling nervous and excitable, change in how you act;
• Mouth irritation or mouth sores, redness or white patches in mouth or throat;
• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat;
• Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, pain with passing urine, mouth sores, or wound that will not heal;
• Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit;
• Signs of low potassium levels like muscle pain or weakness, muscle cramps, or a heartbeat that does not feel normal;
• Signs of a weak adrenal gland like a very bad upset stomach, very bad dizziness, muscle weakness, feeling very tired, mood changes, not hungry, or weight loss;
• Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight;
• Weight gain;
• Very bad breathing problems. Sometimes, this may be life-threatening. If you have trouble breathing, breathing that is worse, wheezing, or coughing after using Wixela Inhub (fluticasone and salmeterol inhalation powder), use a rescue inhaler and get medical help right away.

Wixela Inhub Precautions

Wixela Inhub does not act quickly enough to provide relief from a sudden attack of breathlessness or wheezing due to asthma or COPD. A fast acting ‘reliever’ medicine, such as salbutamol should be used for any sudden attacks of breathlessness or wheezing (e.g., asthma attacks). Do not use Wixela Inhub if you are allergic to fluticasone propionate, salmeterol xinafoateor, lactose or to any other ingredients in this medication or if you have problems of your heart beating fast and/or irregularly; have an untreated fungal, bacterial or tuberculosis infection. Before you start taking this medication, tell your doctor about your medical history, including if you have eye problems such as glaucoma, cataracts, blurry vision or other changes in vision; are suffering from any chest infection (cold, bronchitis); have ever had to stop taking another medication for your breathing problems because you were allergic to it or it caused problems; have been told you are allergic to lactose (milk sugar) or milk protein; ever had a yeast infection (thrush) in your mouth; are having treatment for a thyroid condition; have diabetes; have high blood pressure; have heart problems; have had tuberculosis (TB) infections; are taking other “steroids” by mouth or by inhalation; are pregnant, planning to become pregnant or breastfeeding; are taking a medicine called ketoconazole, used to treat fungal infection; are taking medicines used to treat HIV infection (e.g. ritonavir, atazanavir, indinavir, and cobicistat containing products); have liver problems or cirrhosis. Tell your doctor about all the medications you take including prescription, OTC, herbal supplements and vitamins. There may be a drug interaction between Wixela Inhub and other medications. You should avoid coming into contact with anyone who has measles, chicken pox, cold, or the flu while taking an ICS. If you or your child is exposed, tell your doctor right away. Tell your doctor immediately if there is a change in your symptoms such as more coughing, attacks of wheezing, chest tightness, or an unusual increase in the severity of the breathlessness; you wake up at night with chest tightness, wheezing or shortness of breath; use increasing amounts of your fast acting ‘reliever’ medicine. These could be warning signs that your condition may be worsening. Do not stop taking Wixela Inhub without talking to your doctor. Tell your doctor immediately if you notice symptoms of a ‘flare up”. Patients with COPD have a higher chance of getting pneumonia (a lung infection).

Do I need a prescription to order Wixela Inhub?

Yes, a prescription is required from your physician to order Wixela Inhub.