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Brand Giotrif 30 mg from Canada by Boehringer Ingelheim

The brand Giotrif 30 mg comes from Canada by Boehringer Ingelheim. It is available in the quantity of 28 tablets.

Gilotrif (Afatinib dimaleate) Information

Gilotrif, which contains the active ingredient afatinib, is a targeted therapy medication classified as a kinase inhibitor. It is primarily used for the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) whose tumors have specific non-resistant epidermal growth factor receptor (EGFR) mutations. It is also indicated for patients with squamous NSCLC that has progressed after platinum-based chemotherapy. By targeting the genetic drivers of the tumor, Gilotrif helps stall the growth and spread of cancer cells more effectively than traditional chemotherapy in eligible patients. It is taken by mouth as a tablet, typically once daily.

The mechanism of action involves the irreversible inhibition of the ErbB family of tyrosine kinases. Unlike some other inhibitors that only target one receptor, afatinib binds permanently to EGFR (ErbB1), HER2 (ErbB2), and ErbB4. These receptors signal cells to grow and multiply. In certain lung cancers, these signals are stuck in the "on" position. By covalently bonding to these receptors and blocking their signaling, Gilotrif shuts down the pathway, leading to tumor shrinkage and a delay in cancer progression.

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Do I need a prescription to order Giotrif 30 mg ?

Yes, a prescription is required from your physician to order Giotrif 30 mg.