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Brand Silenor 6 mg from Canada by Paladin

The brand Silenor 6 mg comes from Canada manufactured by Paladin. It is available in the quantity of 30 and 90 tablets.

Silenor Information

Silenor (Doxepin) is a low-dose formulation of Doxepin specifically indicated for insomnia. While higher doses of generic Doxepin are used for depression and anxiety, Silenor is formulated only for sleep maintenance. Doxepin hydrochloride is a medication that belongs to the tricyclic antidepressant class. While its mechanism of action is not fully understood, doxepin is believed to work through two major mechanisms. It acts as a potent antagonist at the histamine receptors and muscarinic acetylcholine receptors, while also inhibiting the reuptake of serotonin and norepinephrine at the neuronal synapse. At very low doses, its high affinity for histamine receptors drives its sedative effects, making it useful in people with insomnia, whereas higher doses are required to achieve the neurotransmitter modulation necessary for its antidepressant effects.

Insomnia is a condition in which an individual has difficulty falling asleep and staying asleep throughout the night, often resulting in a lack of restorative sleep. Doxepin helps in this instance by blocking the wake-promoting effects of histamine in the brain, which appears to stabilize the sleep cycle and prevent early morning awakenings. Major depressive disorder involves complex shifts in brain chemistry that can lead to persistent low mood or excessive worry. This medication helps in treating depression by increasing the concentration of serotonin and norepinephrine in the brain, which may suggest an improvement in emotional regulation and a reduction in psychological distress. Doxepin’s effects on neurotransmitters in the brain also account for why it may be used for the treatment of anxiety disorders. It may also be used to treat itching associated with chronic hives (urticaria) or atopic dermatitis, due to its effects on histamine receptors.

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Do I need a prescription to order Silenor 6 mg ?

Yes, a prescription is required from your physician to order Silenor 6 mg.