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Cotellic Information

Cotellic (Cobimetinib Fumarate) is used alone to treat a specific type of blood cancer in adults called histiocytic neoplasms. This rare illness occurs when a type of white blood cell, called histiocytes, builds up in specific tissues and organs. Cotellic is used in combination with Zelboraf to treat metastatic melanoma. This condition is a type of skin cancer that spreads to other parts of the body and can't be removed by surgery. Kinase inhibitors like Cobimetinib Fumarate block tyrosine kinases, a chemical that sends growth signals in the cells. Cotellic is used only if your tumor has a specific genetic marker, for which your doctor will test.

Cotellic Side Effects

The most common side effects of Cotellic may include tiredness, nausea, upset stomach, dry skin, and rash. Call your doctor right away if you have any of the severe side effects, such as:
• Easy bruising or bleeding;
• Signs of an allergic reaction, such as rash, breathing difficulties, or itching or swelling of the face, tongue, or throat;
• Unexplained muscle pain;
• Vision changes

Cotellic Precautions

Do not use Cotellic if you are allergic to Cobimetinib Fumarate or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have a blood clotting disorder, a muscle disorder, or heart disease; have skin problems unrelated to melanoma; have a history of eye problems, think you may be pregnant or plan to become pregnant; are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Cotellic and other medications, like amiodarone, clarithromycin, cyclosporine, tenofovir, and isoniazid. Do not use Cotellic if you are pregnant or planning to become pregnant without informing your doctor. Taking Cobimetinib Fumarate in pregnancy can harm your unborn baby. Use effective birth control to prevent pregnancy while taking Cotellic and for at least two weeks after your last dose.

Do not use Cotellic while breastfeeding without talking to your doctor. It is unknown if Cobimetinib Fumarate passes into your breastmilk or if it may harm nursing infants. Do not breastfeed while using this medicine and for at least two weeks after your last dose. Cobimetinib may affect fertility in men or women. It is unknown if this drug is safe for use in children below 18 years of age. Use your medicine exactly as prescribed by your doctor. This drug is often given in a 28-day cycle. You may only need to use this drug for the first 21 days of each cycle. Your doctor will determine how long it will take to treat you with Cotellic. You may take the drug with or without food. If you vomit shortly after taking a dose, do not take another dose. Follow your normal dosing schedule. Check your skin regularly while using Cotellic. Inform your doctor if you notice new skin changes such as redness, warts, or sores that will not heal. This drug can increase your sensitivity to sunlight. Wear protective clothing and use sunscreen of SPF 30 or higher outdoors. Store this medication at room temperature and keep it out of the reach of children.

BigMountainDrugs.com supplies only genuine Cotellic from Canada shipped using the Canadian packaging. This Cotellic is manufactured by Genetech Inc. (a member of Roche Group), the worldwide manufacturer of Cotellic. This offer is neither endorsed nor authorized by Genetech Inc. (the United States and Canadian distributor of Cotellic). BigMountainDrugs.com has no affiliation whatsoever with Genetech Inc.

Do I need a prescription to order Cotellic?

Yes, a prescription is required from your physician to order Cotellic.