0

Home > Drug Category > Irritable Bowel Syndrome > Trulance and Equivalent

Trulance Information

Trulance (Plecanatide) is used to treat irritable bowel syndrome with constipation (IBS-C) in adults. IBS-C is when people have irritable bowel syndrome and experience constipation instead of diarrhea. IBS-C can cause symptoms including abdominal pain, bloating, and changes in bowel habits. Constipation occurs when a person does not pass bowel movements often enough, typically fewer than three times a week. Symptoms of IBS-C include straining, gas, infrequent bowel movements, abdominal pain, hard or uncomfortable bowel movements, and secondary health issues like hemorrhoids. Trulance is also used to treat chronic idiopathic constipation (CIC). CIC is a long-lasting constipation with an unknown cause. IBS-C and CIC have similar symptoms. Nausea, frequent stomach ache that goes away after you poop, and loose watery stools between bouts of constipation are the differentiating symptoms between IBS-C and CIC. Guanylate cyclase-C agonist medications like Plecanatide work by increasing fluid in the digestive tract. This softens stools, increases the speed of food and waste traveling through the digestive system, and increases the frequency of bowel movements. Trulance also reduces the discomfort that often occurs with long-term constipation by decreasing the sensitivity of pain-sensing nerves in the digestive system. You may experience some level of improvement within the first week of using Trulance.

Trulance Side Effects

The most common side effects of Trulance may include common cold; diarrhea; dizziness; nausea; headache; Call your doctor right away if you have any of the serious side effects such as:
• Severe diarrhea;
• Signs of an allergic reaction, e.g., abdominal cramps, hives, swelling of the face and throat, difficulty breathing, nausea and vomiting

Trulance Precautions

Do not use Trulance if you are allergic to Plecanatide or any other ingredients in this medication. Before you start taking this medication, tell your doctor about your medical history, including if you have bowel blockage; are pregnant, think you may be pregnant or plan to become pregnant; are breastfeeding, or are planning to breastfeed. Tell your doctor about all the medications you take, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Trulance and other medications. Do not use Trulance if you are pregnant or planning to become pregnant. It is not known if this medication will harm your unborn baby. Do not use Trulance while breastfeeding without talking to your doctor. It is not known if Plecanatide passes into your breastmilk. Do not give this drug to children less than 18 years old. It may harm them. Use your medicine exactly as prescribed by your doctor. Do not stop or change the dose of this medicine without talking to your doctor. You may take Trulance with or without food. Swallow the tablet whole. If you cannot swallow the tablet whole, you may crush and mix it with a spoonful of water or applesauce. Swallow the mixture immediately. Do not save it for later use. Trulance tablets mixed with water may also be administered through a nasogastric feeding tube using a catheter-tipped syringe. Plecanatide may cause dehydration. Contact your doctor if you experience symptoms of dehydration, such as increased thirst, decreased urine or tear production, headaches, or dizziness. Keep the tablets in their original package till you are ready to take one. Store at room temperature, away from moisture and heat.

Do I need a prescription to order Trulance?

Yes, a prescription is required from your physician to order Trulance.