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Home > Drug Category > Heart Medication > Vyndamax and Equivalent

Vyndamax Information

Vyndamax (Tafamidis) is a medication specifically used to treat a serious and progressive heart condition called transthyretin-mediated amyloidosis with cardiomyopathy. It is used to reduce the risk of death and hospital admission in individuals with this condition. Vyndamax, with the active ingredient tafamidis, is a medication from the class of drugs known as transthyretin stabilizers. Transthyretin-mediated amyloidosis with cardiomyopathy is caused by the misfolding of a protein called transthyretin (TTR), which then breaks apart and forms amyloid deposits in the heart. These deposits cause the heart muscle to stiffen, making it difficult to pump blood effectively. Vyndamax helps in this disease by acting as a kinetic stabilizer. It binds to the transthyretin protein, essentially holding its structure together and preventing it from breaking apart. By stabilizing the transthyretin protein, it appears to slow down the formation of new amyloid deposits in the heart. This action is intended to reduce the risk of death and hospitalization due to heart problems for those with transthyretin amyloid cardiomyopathy, offering a way to manage a condition that was once considered fatal within just a few years.

Vyndamax Side Effects

Possible common side effects of this medicine include body weakness, lethargy, congested nose, feeling unbalanced when standing or walking, clouding of the lens in your eye, constipation, diarrhea, and body itching. Contact your doctor if these common side effects persist or worsen. Stop taking this medicine and contact your doctor immediately if you experience any serious side effects, including the following:
• Allergic reactions such as breathing difficulties, hives, swelling of the face, mouth, tongue, lips, or throat;
• Frequent and painful urination, pain in the lower abdomen, or other symptoms of bladder infection

Inform your doctor about any other side effects you notice that are not listed here.

Vyndamax Precautions

Do not use this medicine if you are allergic to tafamidis, the inactive ingredients in Vyndamax, or any other medicine. Before using this medication, ensure you inform your doctor about any medical conditions you previously or currently have, including the following:
• History of organ transplant;
• Kidney disease;
• Liver disease

Do not use this medicine during pregnancy or while breastfeeding. Tell your doctor right away if you become pregnant while taking this medication. Suppose you are a woman of childbearing age. In that case, you should use appropriate birth control methods while taking this medicine and also for one month after stopping Vyndamax. Tafamidis may interact with other medications or substances, such as diuretics, methotrexate, olmesartan, rosuvastatin, and sedative drugs. Therefore, inform your healthcare provider about all the medicines, including herbal supplements, that you are taking before using Vyndamax to prevent potential drug interactions.

Take one capsule of Vyndamax by mouth, once a day, as directed by your doctor or as stated in the medication leaflet. You can take it with or without food. Swallow the capsule whole; do not crush, cut, or chew it. Do not double the dose to make up for a missed capsule. Keep using the medication regularly, since it works best when taken long-term to control transthyretin amyloid cardiomyopathy. Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do I need a prescription to order Vyndamax?

Yes, a prescription is required from your physician to order Vyndamax.