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Brand Emend 80 mg from Merck Canada

The brand Emend 80 mg tablets come from Canada manufactured by Merck. It is available in the quantity of 2 tablets.

Emend Information

Emend (Aprepitant) is primarily used for the prevention of acute and delayed nausea and vomiting associated with highly and moderately emetogenic chemotherapy. Chemotherapy is intended to destroy malignant cells, but it often triggers the release of neurotransmitters that signal the brain to initiate vomiting. This defense mechanism can be physically exhausting and may compromise the individual’s ability to complete their treatment. This medication is also used in the prevention of nausea and vomiting after a surgical operation.

The active ingredient is aprepitant, a potent and selective antagonist of the substance P/neurokinin 1 (NK1) receptor. This medication works by selectively inhibiting the binding of substance P, a naturally occurring neuropeptide, to neurokinin receptors located in the brainstem's emetic center and the gastrointestinal tract. By blocking the NK1 receptors, aprepitant interrupts these specific signaling pathways before the vomiting reflex is fully activated. This is particularly effective for the delayed phase of chemotherapy-induced nausea, which often persists for several days after treatment and remains resistant to many standard antiemetics. Consequently, it helps maintain the patient’s nutritional intake and quality of life during intensive medical therapy.

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Do I need a prescription to order Emend 80 mg ?

Yes, a prescription is required from your physician to order Emend 80 mg.