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Brand Lynparza 100 mg from Australia by AstraZeneca

The brand Lynparza 100 mg comes from Australia manufactured by AstraZeneca. It is available in the quantity of 112 tablets.

Lynparza Information

Lynparza (Olaparib) is used for several specific cancer treatment scenarios, often requiring a companion diagnostic test to detect specific genetic markers. Lynparza is typically used as a maintenance therapy for the treatment of cancer of the ovaries, fallopian tube, or primary peritoneal cancer and can be taken alone or in combination with bevacizumab. It is administered after the initial treatment phase has ended, to prevent the progression of the cancer or keep the cancer from coming back. In conjunction with bevacizumab, it is used if your advanced ovarian cancer has tested positive for homologous recombination deficiency and has responded to your first treatment with platinum-based chemotherapy. It may also be used alone in advanced ovarian cancer that has tested positive for a BRCA mutation and has responded to initial treatment with platinum-based chemotherapy.

It is also used in the treatment of breast cancer, specifically for HER2-negative patients with a germline BRCA mutation. It is used in early-stage breast cancers with a high risk of recurrence, where it is given after surgery. You should have received chemotherapy medicines before or after surgery to remove the tumor. It is also used in advanced breast cancer that has spread to other parts of the body (metastatic). Following the diagnosis, you would have received chemotherapy before or after the cancer spread. If your cancer is hormone receptor-positive, you should have already undergone hormone therapy, or you are not a good candidate for that treatment. Lynparza can also treat pancreatic cancer when it has spread (adenocarcinoma) and is associated with a specific BRCA gene mutation. It's usually used as maintenance treatment after a patient's cancer has not progressed during at least their first 16 weeks of platinum-based chemotherapy.

Furthermore, Lynparza is beneficial in treating metastatic castration-resistant prostate cancer driven by specific genetic mutations in the homologous recombination repair pathway. It's used when the cancer has metastasized and continues to progress despite standard treatments like hormonal therapy (lowering testosterone) or other cancer medicines known as enzalutamide or abiraterone. Lynparza is also approved for the treatment of advanced prostate cancers with specific mutations in the BRCA genes. When cancer spreads to other parts of the body and no longer responds to conventional treatment, including testosterone suppression, Lynparza is often combined with abiraterone and prednisone or prednisolone.

Lynparza (olaparib) is a fascinating drug, particularly because it represents a shift toward more targeted cancer treatments. It contains the active ingredient olaparib, a potent PARP (poly ADP-ribose polymerase) inhibitor. Olaparib inhibits the PARP enzyme, which repairs single-strand DNA breaks. While healthy cells typically have functional backup repair pathways (like homologous recombination), cancer cells with BRCA mutations lack these alternatives. By inhibiting PARP, olaparib forces these cancer cells to accumulate catastrophic genomic damage that they cannot fix, ultimately triggering programmed cell death (apoptosis). This targeted approach appears highly effective at preventing disease progression after initial chemotherapy, as it specifically exploits the tumor's preexisting genetic weakness while sparing a significant portion of healthy tissue. Consequently, it extends progression-free survival and, in some clinical settings, has shown a meaningful impact on overall survival in patients with high-risk genetic profiles.

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Do I need a prescription to order Lynparza 100 mg ?

Yes, a prescription is required from your physician to order Lynparza 100 mg.